"Towards toxicity assessment without animals"
Wednesday 21st – Friday 23rd September 2011
Tampere, Scandic Rosendahl, Tampere, Finland
Programme:
Wednesday, September 21, 2011
08:00 –
REGISTRATION
09:00 – 09:15
Opening
Tuula Heinonen, FICAM, University of Tampere, FI
09:15 – 12:00
Session 1: Status of EU-projects and new developments to replace animal experiments
Chair: Horst Spielmann, Freie Universität Berlin, DE
09:15 – 10:00
Status of EU-projects and new developments in reproductive toxicity assessment
Horst Spielmann, Freie Universität Berlin, DE
10:00 – 10:30
Carcinogenicity and mutagenicity
Tuula Heinonen, FICAM, University of Tampere, FI
10:30 – 10:45
COFFEE BREAK
10:45 – 11:15
Acute toxicity
Cecilia Clemedson, AdvocoTox consulting AB, SE
11:15 – 11:45
ECVAM prevalidation study on skin sensitisation alternatives: progress update
David Basketter, DABMEB Consultancy Ltd, Sharnbrook, UK
11:45 – 12:15
Toxicokinetics
Olavi Pelkonen, University of Oulu, FI
12:15 – 13:00
LUNCH (SSCT board meeting)
13:00 – 18:00
Session 2: Impact of the Council adopted Updated Directive 86/609/EEC 2010/63/EU
Chair: Joachim Kreysa, ECVAM, JRC, IT and Tuula Heinonen, FICAM, University of Tampere, FI
13:00 – 13:45
EU-perspective
Susanna Louhimies, EU - DG Environment, BE
13:45 – 14:30
ECVAM-perspective
Joachim Kreysa, ECVAM, JRC, IT
14:30 – 15:15
Implementation in Finland
Kai Pelkonen, Kai Pelkonen Consulting Ltd, FI
15:15 – 15:45
COFFEE BREAK AND POSTER VIEWING
15:45 – 16:15
Use of non-animal models in regulatory science: challenges & opportunities
Derek Knight, ECHA, FI
16:15 – 16:45
Neuronal cells differentiated from human embryonic cells and iPS cells as building blocks for functional models
Magda Forsberg, Karolinska Institutet, SE
16:45 – 17:15
Nanoparticles as ecotoxicological threat
Anne Kahru, National Institute of Chemical Physics and Biophysics, EE
17:15 – 17:35
Free presentation
17:35 – 17:55
Free presentation
18:00 – 20:00
GET TOGETHER
Thursday, September 22, 2011
09:00 – 12:30
Session 3: A new paradigm: Away from histopathology based toxicity assessment
Chair: Thomas Hartung, Johns Hopkins University – CAAT, US
09:00 – 09:45
Toxicity testing in the 21st century
Thomas Hartung, Johns Hopkins University – CAAT, US
09:45 - 10:30
Critical toxicity pathways – How to identify?
Robert Kavlock, EPA, US
10:30 – 11:00
COFFEE BREAK
11:00 – 11:45
Critical biomarkers for estimation of acute neurotoxicity by using in vitro models
Anna Forsby, Stockholm University, SE
11:45 – 12:30
How to add metabolism into the in vitro cellular system
Olavi Pelkonen, University of Oulu, FI
12:30 – 13:30
LUNCH
13:30 – 17:30
Session 4: Optimal in vitro cellular model
Chair: Timo Ylikomi, FICAM, University of Tampere , FI
13:30 – 14:00
In vitro - in vivo extrapolation of toxic potencies: basic requirements
Hasso Seibert, University Medical School, Schleswig-Holstein DE
14:00 - 14:30
Optimal matrices
Timo Ylikomi, FICAM, University of Tampere, FI
14:30 - 15:00
A breakthrough in biomaterial development for 2D-3D cellular models
Marjo Yliperttula, University of Helsinki, FI
15:00 – 15:30
COFFEE BREAK AND POSTER VIEWING
15:30 – 15:45
Introduction to the Björn Ekwall Memorial Award Lecture
Hanna Tähti, FICAM, University of Tampere, FI
15:45 – 16:30
The Björn Ekwall Memorial Award Lecture
Placental transporters: models and mechanisms in toxicology
Päivi Myllynen, University of Oulu, FI
16:30 – 18:00
SSCT ANNUAL GENERAL MEETING
18:00 – 19:00
MEETING OF THE NEW SSCT BOARD
19:00
BANQUET
Friday, September 23, 2011
09:00 – 10:20
Session 5: Significance of biological barriers in toxicity risk assessment
Chair: Kirsi Vähäkangas, University of Eastern Finland, FI and Bas Blaauboer, University of Utrecht, NL
09:00 – 09:45
The significance of specific barriers in biokinetics: the consequences for toxicological risk assessment of compounds
Bas Blaauboer, University of Utrecht, NL
09:45 – 10:15
Use of in vitro models of the BBB for the determination of acute and repeated dose toxicity
Romeo Cecchelli, Artois University, Lille, FR
10:15 – 10:45
Placental barrier in toxicology
Kirsi Vähäkangas, University of Eastern Finland, FI
10:45– 11:15
COFFEE BREAK
11:15 – 11:35
Free presentation
11:35 – 11:55
Free presentation
11:55 – 12:15
Free presentation
12:15 – 12:35
Free presentation
12:35 – 12:55
Free presentation
12:55 – 13:00
CLOSING OF THE WORKSHOP
For more information:
http://ficam.fi/en/component/content/article/32-ssct-2011-workshop
